One Study Highlights Benefits of Combined Exercise Program for ALS Patients

A study published in the Journal of Neurology by Alon Kalron and colleagues in May 2021 explored the effects of a 12-week combined aerobic and strength training program on ambulatory patients with amyotrophic lateral sclerosis (ALS). The research aimed to compare this comprehensive exercise approach with a flexibility training program alone, focusing on various health-related symptoms specific to ALS.

The study involved 32 ambulatory ALS patients who were randomly assigned to either the combined aerobic-strength training group or a control group that performed flexibility exercises. Over the course of 12 weeks, both groups participated in two sessions per week. The combined program included recumbent cycling for aerobic training, functional exercises for strength, and stretching for flexibility. The control group engaged in basic stretching exercises at home.

Outcome measures were assessed at three points: before the intervention, after six weeks, and at the end of the 12-week program. The researchers evaluated respiratory function, mobility, fatigue, and quality of life using established scales, including the ALS Functional Rating Scale-Revised (ALSFRS-R) and the Short Form (36) Health Survey (SF-36).

The results were promising. Patients in the combined aerobic-strength training group showed significant improvements in respiratory function, mobility, and overall wellbeing compared to those in the flexibility training group. Specifically, they maintained their abilities in these areas, while the control group experienced a decline. Notably, the combined exercise group reported higher scores in physical functioning, energy levels, and overall wellbeing after the intervention.

However, it is important to note that the sample size was relatively small, and the researchers did not assess the long-term effects of the exercise program after the 12-week period. Additionally, the study did not include separate groups for aerobic and strength training alone, making it difficult to determine the specific benefits of each component.

Despite these factors, the findings suggest that a structured exercise program combining aerobic and strength training may be beneficial for individuals with ALS, particularly in preserving respiratory function and enhancing quality of life. The study adds to the growing body of evidence supporting the role of exercise in managing ALS symptoms and improving patient outcomes.

For those living with ALS, engaging in a tailored exercise program under professional guidance may be a valuable addition to their care plan. As research continues to evolve, it is essential to stay informed about new findings that could enhance the quality of life for ALS patients.